CATH Domain 1r31A02

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.770	3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2
	3.90.770.10	3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2

Superfamily	3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2
Functional Family

1.1.1.88

Hydroxymethylglutaryl-CoA reductase.

based on mapping to UniProt P13702

(R)-mevalonate + CoA + 2 NAD(+) = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.

MVAA_PSEMV

Pseudomonas mevalonii

3-hydroxy-3-methylglutaryl-coenzyme A reductase

PDB	1R31
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-CoA Reductase. Watson, J.M., Steussy, C.N., Burgner, J.W., Lawrence, C.M., Tabernero, L., Rodwell, V.W., Stauffacher, C.V. To be Published