CATH Domain 1qzmA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.8	Helicase, Ruva Protein; domain 3
	1.10.8.60

Domain Context

CATH Clusters

Superfamily	1.10.8.60
Functional Family	Lon protease

Enzyme Information

3.4.21.53

Endopeptidase La.

based on mapping to UniProt P0A9M0

Hydrolysis of proteins in presence of ATP.

-!- ATP hydrolysis is linked with peptide bond hydrolysis. -!- Vanadate inhibits both reactions. -!- A similar enzyme occurs in animal mitochondria. -!- Belongs to peptidase family S16.

UniProtKB Entries (1)

P0A9M0

LON_ECOLI

Escherichia coli K-12

Lon protease

PDB Structure

PDB	1QZM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution. Botos, I., Melnikov, E.E., Cherry, S., Khalatova, A.G., Rasulova, F.S., Tropea, J.E., Maurizi, M.R., Rotanova, T.V., Gustchina, A., Wlodawer, A. J.Struct.Biol.