CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.630.30
Functional Family Histone acetyltransferase

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q06592
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

Q06592
HPA2_YEAST
Saccharomyces cerevisiae S288C
Histone acetyltransferase HPA2

PDB Structure

PDB 1QSO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the histone acetyltransferase Hpa2: A tetrameric member of the Gcn5-related N-acetyltransferase superfamily.
Angus-Hill, M.L., Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V.
J.Mol.Biol.