CATH Classification
Level | CATH Code | Description |
---|---|---|
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3 | Alpha Beta |
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3.40 | 3-Layer(aba) Sandwich |
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3.40.50 | Rossmann fold |
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3.40.50.2020 |
Domain Context
CATH Clusters
Superfamily | 3.40.50.2020 |
Functional Family |
Enzyme Information
2.4.2.8 |
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt Q26997
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.
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2.4.2.22 |
Xanthine phosphoribosyltransferase.
based on mapping to UniProt Q26997
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.
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UniProtKB Entries (1)
Q26997 |
HGXR_TOXGO
Toxoplasma gondii
Hypoxanthine-guanine-xanthine phosphoribosyltransferase
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PDB Structure
PDB | 1QK4 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structures of the Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase Gmp and -Imp Complexes: Comparison of Purine Binding Interactions with the Xmp Complex
Biochemistry
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