CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.190.80
Functional Family PAP-specific phosphatase HAL2-like

Enzyme Information

3.1.3.7
3'(2'),5'-bisphosphate nucleotidase.
based on mapping to UniProt P32179
Adenosine 3',5'-bisphosphate + H(2)O = adenosine 5'-phosphate + phosphate.
-!- Also acts on 3'-phosphoadenylylsulfate, and on the corresponding 2'-phosphates.

UniProtKB Entries (1)

P32179
MET22_YEAST
Saccharomyces cerevisiae S288C
3'(2'),5'-bisphosphate nucleotidase

PDB Structure

PDB 1QGX
External Links
Method X-RAY DIFFRACTION
Organism Saccharomyces
Primary Citation
X-ray structure of yeast Hal2p, a major target of lithium and sodium toxicity, and identification of framework interactions determining cation sensitivity.
Albert, A., Yenush, L., Gil-Mascarell, M.R., Rodriguez, P.L., Patel, S., Martinez-Ripoll, M., Blundell, T.L., Serrano, R.
J.Mol.Biol.
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