CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.330 | Vcp-like ATPase; Chain A, domain 2 |
|
3.10.330.10 |
Domain Context
CATH Clusters
| Superfamily | 3.10.330.10 |
| Functional Family | vesicle-fusing ATPase isoform X1 |
Enzyme Information
| 3.6.4.6 |
Vesicle-fusing ATPase.
based on mapping to UniProt P18708
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.
|
UniProtKB Entries (1)
| P18708 |
NSF_CRIGR
Cricetulus griseus
Vesicle-fusing ATPase
|
PDB Structure
| PDB | 1QDN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein.
Nat.Cell Biol.
|
