CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.50 | FAD/NAD(P)-binding domain |
|
3.50.50.60 | FAD/NAD(P)-binding domain |
Domain Context
CATH Clusters
| Superfamily | FAD/NAD(P)-binding domain |
| Functional Family | NADPH-dependent 2,4-dienoyl-CoA reductase |
Enzyme Information
| 1.3.1.34 |
2,4-dienoyl-CoA reductase (NADPH).
based on mapping to UniProt P42593
Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5- tetradehydroacyl-CoA + NADPH.
-!- Best substrates for reduction contain a 2,4-diene structure with chain length C(8) or C(10).
|
UniProtKB Entries (1)
| P42593 |
FADH_ECOLI
Escherichia coli K-12
2,4-dienoyl-CoA reductase
|
PDB Structure
| PDB | 1PS9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure and reaction mechanism of Escherichia coli 2,4-dienoyl-CoA reductase
J.Biol.Chem.
|
