CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.260 | Galactose-binding domain-like |
Domain Context
CATH Clusters
| Superfamily | Galactose-binding domain-like |
| Functional Family | proprotein convertase subtilisin/kexin type 7 |
Enzyme Information
| 3.4.21.61 |
Kexin.
based on mapping to UniProt P13134
Cleavage of -Lys-Arg-|-Xaa- and -Arg-Arg-|-Xaa- bonds to process yeast alpha-factor pheromone and killer toxin precursors.
-!- Calcium activated. -!- Inhibited by p-mercuribenzoate. -!- Belongs to peptidase family S8. -!- Formerly EC 3.4.22.23.
|
UniProtKB Entries (1)
| P13134 |
KEX2_YEAST
Saccharomyces cerevisiae S288C
Kexin
|
PDB Structure
| PDB | 1OT5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Saccharomyces |
| Primary Citation |
2.4 A Resolution Crystal Structure of the Prototypical Hormone-Processing Protease Kex2 in Complex with an Ala-Lys-Arg Boronic Acid Inhibitor
Biochemistry
|