CATH Domain 1o7hA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.380	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1
	3.90.380.10	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1
Functional Family	Naphthalene 1,2-dioxygenase system, large oxygenase component

Enzyme Information

1.14.12.12

Naphthalene 1,2-dioxygenase.

based on mapping to UniProt P0A110

Naphthalene + NADH + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+).

-!- Comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.3), an iron-sulfur oxygenase, and ferredoxin.

UniProtKB Entries (1)

P0A110

NDOB_PSEPU

Pseudomonas putida

Naphthalene 1,2-dioxygenase system, large oxygenase component

PDB Structure

PDB	1O7H
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Naphthalene Dioxygenase: Side-on Binding of Dioxygen to Iron Karlsson, A., Parales, J.V., Parales, R.E., Gibson, D.T., Eklund, H., Ramaswamy, S. Science