CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1970 |
Domain Context
CATH Clusters
Superfamily | 3.40.50.1970 |
Functional Family | Phosphoribosylaminoimidazole carboxylase |
Enzyme Information
5.4.99.18 |
5-(carboxyamino)imidazole ribonucleotide mutase.
based on mapping to UniProt Q9WYS7
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxylate.
-!- In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates. -!- In the absence of EC 6.3.2.6, the reaction is reversible. -!- The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation.
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UniProtKB Entries (1)
Q9WYS7 |
PURE_THEMA
Thermotoga maritima MSB8
N5-carboxyaminoimidazole ribonucleotide mutase
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PDB Structure
PDB | 1O4V |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77 A resolution
Proteins
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