CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10860 | Leucine Dehydrogenase, chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Leucine Dehydrogenase, chain A, domain 1 |
| Functional Family | Shikimate dehydrogenase (NADP(+)) |
Enzyme Information
| 1.1.1.25 |
Shikimate dehydrogenase.
based on mapping to UniProt Q58484
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
|
UniProtKB Entries (1)
| Q58484 |
AROE_METJA
Methanocaldococcus jannaschii DSM 2661
Shikimate dehydrogenase (NADP(+))
|
PDB Structure
| PDB | 1NVT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of shikimate 5-dehydrogenase (SDH) bound to NADP: insights into function and evolution
Structure
|
