CATH Classification

Domain Context

CATH Clusters

Superfamily NADP-dependent oxidoreductase domain
Functional Family 2,5-diketo-D-gluconic acid reductase A

Enzyme Information

1.1.1.274
2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming).
based on mapping to UniProt Q46857
2-dehydro-D-gluconate + NADP(+) = 2,5-didehydro-D-gluconate + NADPH.
-!- The enzyme is involved in the catabolism of 2,5-didehydrogluconate. -!- cf. EC 1.1.1.346.

UniProtKB Entries (1)

Q46857
DKGA_ECOLI
Escherichia coli K-12
2,5-diketo-D-gluconic acid reductase A

PDB Structure

PDB 1MZR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Escherichia coli DkgA, a broad-specificity aldo-keto reductase.
Jeudy, S., Monchois, V., Maza, C., Claverie, J.M., Abergel, C.
Proteins