CATH Classification
Domain Context
CATH Clusters
| Superfamily | Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
| Functional Family |
Enzyme Information
| 1.1.1.27 |
L-lactate dehydrogenase.
based on mapping to UniProt E8ME30
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.
|
UniProtKB Entries (1)
| E8ME30 |
LDH2_BIFL2
Bifidobacterium longum subsp. longum JCM 1217
L-lactate dehydrogenase 2
|
PDB Structure
| PDB | 1LTH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
T and R states in the crystals of bacterial L-lactate dehydrogenase reveal the mechanism for allosteric control.
Nat.Struct.Biol.
|
