CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.160 | 3 Solenoid |
|
2.160.20 | Pectate Lyase C-like |
|
2.160.20.60 | Glutamate synthase, alpha subunit, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Glutamate synthase, alpha subunit, C-terminal domain |
| Functional Family | Ferredoxin-dependent glutamate synthase, chloroplastic |
Enzyme Information
| 1.4.7.1 |
Glutamate synthase (ferredoxin).
based on mapping to UniProt P55038
2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H(+).
-!- The protein is composed of two domains, one hydrolyzing L-glutamine to NH(3) and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH(3) with 2-oxoglutarate to produce a second molecule of L-glutamate. -!- The NH(3) is channeled through a 24 A channel in the active protein. -!- No hydrolysis of glutamine takes place without ferredoxin and 2-oxoglutarate being bound to the protein.
|
UniProtKB Entries (1)
| P55038 |
GLTS_SYNY3
Synechocystis sp. PCC 6803 substr. Kazusa
Ferredoxin-dependent glutamate synthase 2
|
PDB Structure
| PDB | 1LM1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural studies on the synchronization of catalytic centers in glutamate synthase
J.BIOL.CHEM.
|
