CATH Domain 1kwmB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.340	Metallocarboxypeptidase-like

Domain Context

CATH Clusters

Superfamily	Metallocarboxypeptidase-like
Functional Family	Carboxypeptidase A

Enzyme Information

3.4.17.2

Carboxypeptidase B.

based on mapping to UniProt P15086

Preferential release of a C-terminal lysine or arginine amino acid.

-!- Isolated from cattle, pig and dogfish pancreas, and other sources, including skin fibroblasts and adrenal medulla. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.2 and EC 3.4.12.3.

UniProtKB Entries (1)

P15086

CBPB1_HUMAN

Homo sapiens

Carboxypeptidase B

PDB Structure

PDB	1KWM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Pichia
Primary Citation	Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI). Barbosa Pereira, P.J., Segura-Martin, S., Oliva, B., Ferrer-Orta, C., Aviles, F.X., Coll, M., Gomis-Ruth, F.X., Vendrell, J. J.Mol.Biol.