CATH Classification

Domain Context

CATH Clusters

Superfamily Galactose-binding domain-like
Functional Family Ephrin type-B receptor 2

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P54763
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P54763
EPHB2_MOUSE
Mus musculus
Ephrin type-B receptor 2

PDB Structure

PDB 1KGY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of an Eph receptor-ephrin complex.
Himanen, J.P., Rajashankar, K.R., Lackmann, M., Cowan, C.A., Henkemeyer, M., Nikolov, D.B.
Nature
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