CATH Classification

Domain Context

CATH Clusters

Superfamily Severin
Functional Family gelsolin isoform X1

Enzyme Information

UniProtKB Entries (1)

P06396
GELS_HUMAN
Homo sapiens
Gelsolin

PDB Structure

PDB 1KCQ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type.
Kazmirski, S.L., Isaacson, R.L., An, C., Buckle, A., Johnson, C.M., Daggett, V., Fersht, A.R.
Nat.Struct.Biol.
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