CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.920 | Histone Acetyltransferase; Chain A |
|
1.20.920.10 | Bromodomain-like |
Domain Context
CATH Clusters
| Superfamily | Bromodomain-like |
| Functional Family | Histone acetyltransferase p300 |
Enzyme Information
| 2.3.1.48 |
Histone acetyltransferase.
based on mapping to UniProt Q92793
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
|
UniProtKB Entries (1)
| Q92793 |
CBP_HUMAN
Homo sapiens
CREB-binding protein
|
PDB Structure
| PDB | 1JSP |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Mol.Cell
|
