CATH Domain 1iy7A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.630	Aminopeptidase
	3.40.630.10	Zn peptidases

Domain Context

CATH Clusters

Superfamily	Zn peptidases
Functional Family	Carboxypeptidase A1

Enzyme Information

3.4.17.1

Carboxypeptidase A.

based on mapping to UniProt P00730

Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.

-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.

UniProtKB Entries (1)

P00730

CBPA1_BOVIN

Bos taurus

Carboxypeptidase A1

PDB Structure

PDB	1IY7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Sulfamide-Based Inhibitors for Carboxypeptidase A. Novel Type Transition State Analogue Inhibitors for Zinc Proteases Park, J.D., Kim, D.H., Kim, S.J., Woo, J.R., Ryu, S.E. J.Med.Chem.