CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.270
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P96022
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P96022
DPO4_SACSO
Saccharolobus solfataricus
DNA polymerase IV

PDB Structure

PDB 1IM4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain.
Zhou, B.L., Pata, J.D., Steitz, T.A.
Mol.Cell
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