CATH Classification

Domain Context

CATH Clusters

Superfamily GAD-like domain
Functional Family Aspartate--tRNA ligase

Enzyme Information

6.1.1.12
Aspartate--tRNA ligase.
based on mapping to UniProt P21889
ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).

UniProtKB Entries (1)

P21889
SYD_ECOLI
Escherichia coli K-12
Aspartate--tRNA ligase

PDB Structure

PDB 1IL2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of an AspRS-tRNA(Asp) complex reveals a tRNA-dependent control mechanism.
Moulinier, L., Eiler, S., Eriani, G., Gangloff, J., Thierry, J.C., Gabriel, K., McClain, W.H., Moras, D.
EMBO J.