CATH Classification
Level | CATH Code | Description |
---|---|---|
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2 | Mainly Beta |
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2.60 | Sandwich |
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2.60.60 | Lipoxygenase-1 |
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2.60.60.20 | PLAT/LH2 domain |
Domain Context
CATH Clusters
Superfamily | PLAT/LH2 domain |
Functional Family |
Enzyme Information
1.13.11.58 |
Linoleate 9S-lipoxygenase.
based on mapping to UniProt P09186
Linoleate + O(2) = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
-!- A common plant lipoxygenase that oxidizes linoleate and alpha- linolenate, the two most common polyunsaturated fatty acids in plants, by inserting molecular oxygen at the C(9) position with (S)- configuration. -!- The enzyme plays a physiological role during the early stages of seedling growth. -!- The enzyme from Arabidopsis thaliana shows comparable activity toward linoleate and linolenate. -!- EC 1.13.11.12 catalyzes a similar reaction at another position of these fatty acids.
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UniProtKB Entries (1)
P09186 |
LOX3_SOYBN
Glycine max
Seed linoleate 9S-lipoxygenase-3
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PDB Structure
PDB | 1IK3 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Three-dimensional structure of a purple lipoxygenase.
J.Am.Chem.Soc.
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