CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.367.20
Functional Family Phosphotransferase

Enzyme Information

2.7.1.1
Hexokinase.
based on mapping to UniProt P04807
ATP + D-hexose = ADP + D-hexose 6-phosphate.
-!- D-glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors. -!- ITP and dATP can act as donors.

UniProtKB Entries (1)

P04807
HXKB_YEAST
Saccharomyces cerevisiae S288C
Hexokinase-2

PDB Structure

PDB 1IG8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The high resolution crystal structure of yeast hexokinase PII with the correct primary sequence provides new insights into its mechanism of action.
Kuser, P.R., Krauchenco, S., Antunes, O.A., Polikarpov, I.
J.Biol.Chem.