CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1050 | Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 |
|
1.20.1050.10 |
Domain Context
CATH Clusters
| Superfamily | 1.20.1050.10 |
| Functional Family | Transcriptional regulator URE2 |
Enzyme Information
| 1.8.4.- |
With a disulfide as acceptor.
based on mapping to UniProt P23202
|
| 1.11.1.9 |
Glutathione peroxidase.
based on mapping to UniProt P23202
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
|
UniProtKB Entries (1)
| P23202 |
URE2_YEAST
Saccharomyces cerevisiae S288C
Transcriptional regulator URE2
|
PDB Structure
| PDB | 1HQO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p.
Proc.Natl.Acad.Sci.USA
|
