CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | flavin reductase (NADPH) |
Enzyme Information
| 1.5.1.30 |
Flavin reductase (NADPH).
based on mapping to UniProt P30043
Reduced riboflavin + NADP(+) = riboflavin + NADPH.
-!- The enzyme from Entamoeba histolytica reduces riboflavin and galactoflavin, and, more slowly, FMN and FAD. -!- NADH is oxidized more slowly than NADPH. -!- Formerly EC 1.6.8.2.
|
| 1.3.1.24 |
Biliverdin reductase.
based on mapping to UniProt P30043
Bilirubin + NAD(P)(+) = biliverdin + NAD(P)H.
|
UniProtKB Entries (1)
| P30043 |
BLVRB_HUMAN
Homo sapiens
Flavin reductase (NADPH)
|
PDB Structure
| PDB | 1HE3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Nat.Struct.Biol.
|