CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.760 | Cytochrome Bc1 Complex; Chain D, domain 2 |
|
1.10.760.10 | Cytochrome c-like domain |
Domain Context
CATH Clusters
| Superfamily | Cytochrome c-like domain |
| Functional Family | L-cysteine S-thiosulfotransferase subunit SoxA |
Enzyme Information
| 2.8.5.2 |
L-cysteine S-thiosulfotransferase.
based on mapping to UniProt Q939U1
(1) [SoxY protein]-L-cysteine + thiosulfate + 2 ferricytochrome c = [SoxY protein]-S-sulfosulfanyl-L-cysteine + 2 ferrocytochrome c + 2 H(+). (2) [SoxY protein]-S-sulfanyl-L-cysteine + thiosulfate + 2 ferricytochrome c = [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + 2 ferrocytochrome c + 2 H(+).
-!- The enzyme is part of the Sox enzyme system, which participates in a bacterial thiosulfate oxidation pathway that produces sulfate. -!- It catalyzes two reactions in the pathway - early in the pathway it attaches a thiosulfate molecule to the sulfur atom of an L-cysteine of a SoxY protein; later it transfers a second thiosulfate molecule to a sulfane group that is already attached to the same cysteine residue.
|
UniProtKB Entries (1)
| Q939U4 |
Q939U4_RHOSU
Rhodovulum sulfidophilum
Cytochrome c
|
PDB Structure
| PDB | 1H32 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for the Oxidation of Thiosulfate by a Sulfur Cycle Enzyme
Embo J.
|
