CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.275 | Fumarase C; Chain B, domain 1 | |
1.10.275.10 | Fumarase/aspartase (N-terminal domain) |
Domain Context
CATH Clusters
Superfamily | Fumarase/aspartase (N-terminal domain) |
Functional Family | Histidine ammonia-lyase |
Enzyme Information
4.3.1.3 |
Histidine ammonia-lyase.
based on mapping to UniProt P21310
L-histidine = urocanate + NH(3).
-!- Member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.23, EC 4.3.1.24 and EC 4.3.1.25. -!- Catalyzes the first step in the degradation of histidine and the product, urocanic acid, is further metabolized to glutamate.
|
UniProtKB Entries (1)
P21310 |
HUTH_PSEPU
Pseudomonas putida
Histidine ammonia-lyase
|
PDB Structure
PDB | 1GKM |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structures of Two Histidine Ammonia-Lyase Modifications and Implications for the Catalytic Mechanism
Eur.J.Biochem.
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