CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.190 | D-Maltodextrin-Binding Protein; domain 2 |
|
3.40.190.80 |
Domain Context
CATH Clusters
| Superfamily | 3.40.190.80 |
| Functional Family | Fructose-1,6-bisphosphatase/inositol-1-monophosphatase |
Enzyme Information
| 3.1.3.11 |
Fructose-bisphosphatase.
based on mapping to UniProt Q57573
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.
|
| 3.1.3.25 |
Inositol-phosphate phosphatase.
based on mapping to UniProt Q57573
Myo-inositol phosphate + H(2)O = myo-inositol + phosphate.
-!- Acts on five of the six isomers of myo-inositol phosphate, all except myo-inositol 2-phosphate, but does not act on myo-inositol bearing more than one phosphate group. -!- It also acts on adenosine 2'-phosphate (but not the 3'- or 5'-phosphates), sn-glycerol 3-phosphate and glycerol 2-phosphate, but does not act on inositol bisphosphates or more phosphorylated inositols.
|
UniProtKB Entries (1)
| Q57573 |
BSUHB_METJA
Methanocaldococcus jannaschii DSM 2661
Fructose-1,6-bisphosphatase/inositol-1-monophosphatase
|
PDB Structure
| PDB | 1G0I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure and catalytic mechanism of the MJ0109 gene product: a bifunctional enzyme with inositol monophosphatase and fructose 1,6-bisphosphatase activities.
Biochemistry
|
