CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1370 | Aspartate/ornithine carbamoyltransferase |
Domain Context
CATH Clusters
Superfamily | Aspartate/ornithine carbamoyltransferase |
Functional Family | Ornithine carbamoyltransferase, mitochondrial |
Enzyme Information
2.1.3.3 |
Ornithine carbamoyltransferase.
based on mapping to UniProt P00480
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
-!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.
|
UniProtKB Entries (1)
P00480 |
OTC_HUMAN
Homo sapiens
Ornithine carbamoyltransferase, mitochondrial
|
PDB Structure
PDB | 1FVO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes.
Biochem.J.
|