CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.450 | Beta-Lactamase |
|
3.30.450.40 | GAF domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.450.40 |
| Functional Family | Free methionine-R-sulfoxide reductase |
Enzyme Information
| 1.8.4.14 |
L-methionine (R)-S-oxide reductase.
based on mapping to UniProt P36088
L-methionine + thioredoxin disulfide + H(2)O = L-methionine (R)-S-oxide + thioredoxin.
-!- Unlike EC 1.8.4.12 this enzyme cannot use peptide-bound methionine (R)-S-oxide as a substrate. -!- Differs from EC 1.8.4.13, in that L-methionine (S)-S-oxide is not a substrate. -!- Formerly EC 1.8.4.5.
|
UniProtKB Entries (1)
| P36088 |
FRMSR_YEAST
Saccharomyces cerevisiae S288C
Free methionine-R-sulfoxide reductase
|
PDB Structure
| PDB | 1F5M |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor.
EMBO J.
|