CATH Classification

Domain Context

CATH Clusters

Superfamily Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family Quinone-dependent D-lactate dehydrogenase

Enzyme Information

1.1.5.12
D-lactate dehydrogenase (quinone).
based on mapping to UniProt P06149
(R)-lactate + a quinone = pyruvate + a quinol.
-!- The enzyme is a peripheral membrane dehydrogenase that participates in respiration. -!- Electrons derived from D-lactate oxidation are transferred to the membrane soluble quinone pool.

UniProtKB Entries (1)

P06149
DLD_ECOLI
Escherichia coli K-12
Quinone-dependent D-lactate dehydrogenase

PDB Structure

PDB 1F0X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme.
Dym, O., Pratt, E.A., Ho, C., Eisenberg, D.
Proc.Natl.Acad.Sci.USA