CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonucleoside hydrolase-like
Functional Family Inosine-uridine preferring nucleoside hydrolase

Enzyme Information

3.2.2.2
Inosine nucleosidase.
based on mapping to UniProt P83851
Inosine + H(2)O = D-ribose + hypoxanthine.
3.2.2.3
Uridine nucleosidase.
based on mapping to UniProt P83851
Uridine + H(2)O = D-ribose + uracil.

UniProtKB Entries (1)

P83851
IUNH_LEIMA
Leishmania major
Inosine-uridine preferring nucleoside hydrolase

PDB Structure

PDB 1EZR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure.
Shi, W., Schramm, V.L., Almo, S.C.
J.Biol.Chem.
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