CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt P56511
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

P56511
LDH_LACPE
Lactobacillus pentosus
L-lactate dehydrogenase

PDB Structure

PDB 1EZ4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces.
Uchikoba, H., Fushinobu, S., Wakagi, T., Konno, M., Taguchi, H., Matsuzawa, H.
Proteins
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