CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.12 | Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 |
|
1.10.12.10 | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
| Functional Family | Probable enoyl-CoA hydratase, mitochondrial |
Enzyme Information
| 4.2.1.17 |
Enoyl-CoA hydratase.
based on mapping to UniProt P14604
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
-!- Acts in the reverse direction. -!- With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).
|
UniProtKB Entries (1)
| P14604 |
ECHM_RAT
Rattus norvegicus
Enoyl-CoA hydratase, mitochondrial
|
PDB Structure
| PDB | 1EY3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion.
Biochemistry
|