CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Outer capsid protein lambda-2 |
Enzyme Information
| 2.7.7.50 |
mRNA guanylyltransferase.
based on mapping to UniProt P11079
GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
-!- Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn.
|
| 2.1.1.56 |
mRNA (guanine-N(7)-)-methyltransferase.
based on mapping to UniProt P11079
S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m(7)G(5')pppR-RNA.
-!- Adds an N(7)-methylguanine cap to mRNA. -!- The nucleoside next to the terminal guanosine may be either guanosine or adenosine.
|
UniProtKB Entries (2)
| P15024 |
LMBD1_REOVD
Mammalian orthoreovirus 3 Dearing
Inner capsid protein lambda-1
|
| P11314 |
SIGM2_REOVL
Mammalian orthoreovirus 1 Lang
Inner capsid protein sigma-2
|
PDB Structure
| PDB | 1EJ6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of the reovirus core at 3.6 A resolution.
Nature
|
