CATH Domain 1eduA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.90

Domain Context

CATH Clusters

Superfamily	1.25.40.90
Functional Family	epsin-2 isoform X1

Enzyme Information

UniProtKB Entries (1)

EPN1_RAT

Rattus norvegicus

Epsin-1

PDB Structure

PDB	1EDU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF). Hyman, J., Chen, H., Di Fiore, P.P., De Camilli, P., Brunger, A.T. J.Cell Biol.