CATH Classification

Domain Context

CATH Clusters

Superfamily Carbohydrate-binding module superfamily 5/12
Functional Family

Enzyme Information

3.2.1.14
Chitinase.
based on mapping to UniProt P20533
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta- linkages in chitin and chitodextrins.
-!- The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act. -!- Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase. -!- Cf. EC 3.2.1.202.

UniProtKB Entries (1)

P20533
CHIA1_BACCI
Bacillus circulans
Chitinase A1

PDB Structure

PDB 1ED7
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of the chitin-binding domain of Bacillus circulans WL-12 chitinase A1.
Ikegami, T., Okada, T., Hashimoto, M., Seino, S., Watanabe, T., Shirakawa, M.
J.Biol.Chem.
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