CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | NADPH:adrenodoxin oxidoreductase, mitochondrial |
Enzyme Information
| 1.18.1.6 |
Adrenodoxin-NADP(+) reductase.
based on mapping to UniProt P08165
2 reduced adrenodoxin + NADP(+) = 2 oxidized adrenodoxin + NADPH.
-!- The enzyme, which transfers electrons from NADPH to adrenodoxin molecules, is the first component in the mitochondrial cytochrome P450 electron transfer systems, and is involved in the biosynthesis of all steroid hormones.
|
UniProtKB Entries (1)
| P08165 |
ADRO_BOVIN
Bos taurus
NADPH:adrenodoxin oxidoreductase, mitochondrial
|
PDB Structure
| PDB | 1E1K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of Adrenodoxin Reductase in Complex with Nadp+ and Nadph Suggesting a Mechanism for the Electron Transfer of an Enzyme Family
Biochemistry
|
