CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1160 | Carbamate kinase |
|
3.40.1160.10 | Acetylglutamate kinase-like |
Domain Context
CATH Clusters
| Superfamily | Acetylglutamate kinase-like |
| Functional Family | Carbamate kinase |
Enzyme Information
| 2.7.2.2 |
Carbamate kinase.
based on mapping to UniProt P95474
ATP + NH(3) + hydrogen carbonate = ADP + carbamoyl phosphate + H(2)O.
-!- The enzyme catalyzes the reversible conversion of carbamoyl phosphate and ADP to ATP and carbamate, which hydrolyzes to ammonia and hydrogen carbonate. -!- The physiological role of the enzyme is to generate ATP.
|
UniProtKB Entries (1)
| P95474 |
CPKA_PYRFU
Pyrococcus furiosus DSM 3638
Carbamate kinase
|
PDB Structure
| PDB | 1E19 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The 1.5-A Resolution Crystal Structure of the Carbamate Kinase-Like Carbamoyl Phosphate Synthetase from the Hyperthermophilic Archaeon Pyrococcus Furiosus, Bound to Adp, Confirms that This Thermoestable Enzyme is a Carbamate Kinase, and Provides Insights Into Substrate Binding and Stability in Carbamate Kinases
J.Mol.Biol.
|
