CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.850 |
Domain Context
CATH Clusters
| Superfamily | 1.10.10.850 |
| Functional Family | Isocitrate lyase |
Enzyme Information
| 4.1.3.30 |
Methylisocitrate lyase.
based on mapping to UniProt P28298
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.
-!- Acts on threo-D(s)-2-methylisocitrate, but not on threo-D(s)- isocitrate, threo-DL-isocitrate or erythro-L(s)-isocitrate.
|
| 4.1.3.1 |
Isocitrate lyase.
based on mapping to UniProt P28298
Isocitrate = succinate + glyoxylate.
-!- The isomer of isocitrate involved is (1R,2S)-1-hydroxypropane-1,2,3- tricarboxylate.
|
UniProtKB Entries (1)
| P28298 |
ACEA_EMENI
Aspergillus nidulans FGSC A4
Isocitrate lyase
|
PDB Structure
| PDB | 1DQU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Emericella |
| Primary Citation |
The crystal structure and active site location of isocitrate lyase from the fungus Aspergillus nidulans.
Structure Fold.Des.
|