CATH Classification

Domain Context

CATH Clusters

Superfamily PurM-like C-terminal domain
Functional Family Phosphoribosylformylglycinamidine cyclo-ligase

Enzyme Information

6.3.3.1
Phosphoribosylformylglycinamidine cyclo-ligase.
based on mapping to UniProt P08178
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.

UniProtKB Entries (1)

P08178
PUR5_ECOLI
Escherichia coli K-12
Phosphoribosylformylglycinamidine cyclo-ligase

PDB Structure

PDB 1CLI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution.
Li, C., Kappock, T.J., Stubbe, J., Weaver, T.M., Ealick, S.E.
Structure Fold.Des.