CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1580 | Nucleoside phosphorylase domain |
Domain Context
CATH Clusters
| Superfamily | Nucleoside phosphorylase domain |
| Functional Family | Purine nucleoside phosphorylase |
Enzyme Information
| 2.4.2.28 |
S-methyl-5'-thioadenosine phosphorylase.
based on mapping to UniProt Q13126
S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha- D-ribose 1-phosphate.
-!- Also acts on 5'-deoxyadenosine and other analogs having 5'-deoxy groups.
|
UniProtKB Entries (1)
| Q13126 |
MTAP_HUMAN
Homo sapiens
S-methyl-5'-thioadenosine phosphorylase
|
PDB Structure
| PDB | 1CB0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis.
Structure Fold.Des.
|