CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.40 | Ribonucleotide Reductase Protein R1; domain 1 | |
1.10.40.30 | Fumarase/aspartase (C-terminal domain) |
Domain Context
CATH Clusters
Superfamily | Fumarase/aspartase (C-terminal domain) |
Functional Family | Adenylosuccinate lyase |
Enzyme Information
4.3.2.2 |
Adenylosuccinate lyase.
based on mapping to UniProt Q9X0I0
(1) N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP. (2) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamide.
-!- Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole.
|
UniProtKB Entries (1)
Q9X0I0 |
PUR8_THEMA
Thermotoga maritima MSB8
Adenylosuccinate lyase
|
PDB Structure
PDB | 1C3U |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
Structure Fold.Des.
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