CATH Classification

Domain Context

CATH Clusters

Superfamily Acetylglutamate kinase-like
Functional Family Carbamate kinase

Enzyme Information

2.7.2.2
Carbamate kinase.
based on mapping to UniProt P0A2X8
ATP + NH(3) + hydrogen carbonate = ADP + carbamoyl phosphate + H(2)O.
-!- The enzyme catalyzes the reversible conversion of carbamoyl phosphate and ADP to ATP and carbamate, which hydrolyzes to ammonia and hydrogen carbonate. -!- The physiological role of the enzyme is to generate ATP.

UniProtKB Entries (1)

P0A2X8
ARCC1_ENTFC
Enterococcus faecium
Carbamate kinase 1

PDB Structure

PDB 1B7B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine.
Marina, A., Alzari, P.M., Bravo, J., Uriarte, M., Barcelona, B., Fita, I., Rubio, V.
Protein Sci.
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