CATH Classification
Domain Context
CATH Clusters
| Superfamily | Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
| Functional Family |
Enzyme Information
| 1.1.1.27 |
L-lactate dehydrogenase.
based on mapping to UniProt P16115
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.
|
UniProtKB Entries (1)
| P16115 |
LDH_THEMA
Thermotoga maritima MSB8
L-lactate dehydrogenase
|
PDB Structure
| PDB | 1A5Z |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization.
Structure
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