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CATH Superfamily 4.10.280.10

Helix-loop-helix DNA-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Helix-loop-helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5786: Aryl hydrocarbon receptor nuclear translocator

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Histone acetyltransferase. [EC: 2.3.1.48]
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
  • A group of enzymes acetylating histones.
  • Several of the enzymes can also acetylate lysines in other proteins.
 18 A0A061IM52 A0A061IM52 A0A061IR94 A0A061IR94 O08785 O08785 O15516 O15516 Q5RAK8 Q5RAK8
(8 more...)
Acetyl-CoA carboxylase. [EC: 6.4.1.2]
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA.
  • Also catalyzes transcarboxylation; the plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA.
 4 B7PUT1 B7PUT1 B7QNX4 B7QNX4
Glycogen(starch) synthase. [EC: 2.4.1.11]
UDP-alpha-D-glucose + ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha- D-glucosyl)(n+1).
  • The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.
  • Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.
  • The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.
  • A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21).
 2 W4ZIC1 W4ZIC1
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