The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Helix-loop-helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 5701: Putative bHLH transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
14 F4IGG9 (/ISS) O81313 (/ISS) Q3E7L7 (/ISS) Q84RD0 (/ISS) Q84WK0 (/ISS) Q8LEG1 (/ISS) Q8S3D2 (/ISS) Q9C707 (/ISS) Q9FHA7 (/ISS) Q9FJ00 (/ISS)
(4 more)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q8LEG1 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q5MP56 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q9FHA7 (/IDA)
Adenylylsulfatase activity GO:0047627
Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate.
1 Q9M041 (/IDA)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
11 O81313 (/TAS) Q84RD0 (/TAS) Q84WK0 (/TAS) Q8LEG1 (/TAS) Q8S3D2 (/TAS) Q9FHA7 (/TAS) Q9FJ00 (/TAS) Q9LXD8 (/TAS) Q9M041 (/TAS) Q9SA82 (/TAS)
(1 more)
Transmitting tissue development GO:0010500
The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.
3 Q9FHA7 (/IGI) Q9LXD8 (/IGI) Q9SND4 (/IGI)
Carpel formation GO:0048462
The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts.
3 Q9FHA7 (/IMP) Q9LXD8 (/IMP) Q9SND4 (/IMP)
Root hair initiation GO:0048766
The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.
3 Q84WK0 (/IMP) Q8LEG1 (/IMP) Q9C707 (/IMP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
2 Q84WK0 (/IEP) Q8LEG1 (/IEP)
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
2 Q84WK0 (/IMP) Q8LEG1 (/IMP)
Sulfur compound metabolic process GO:0006790
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
1 Q9M041 (/IDA)
Purine ribonucleotide metabolic process GO:0009150
The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
1 Q9M041 (/IDA)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
1 F4IGG9 (/IMP)
Polar nucleus fusion GO:0010197
The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.
1 O81313 (/IMP)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q9FHA7 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q8LEG1 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9FHA7 (/IPI)
Gynoecium development GO:0048467
The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.
1 Q9LXD8 (/IGI)
Ovary septum development GO:0080126
The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s).
1 Q9SND4 (/IGI)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
14 Q2QMV9 (/IC) Q2QQ32 (/IC) Q2R0R9 (/IC) Q5TKP7 (/IC) Q651K2 (/IC) Q657D1 (/IC) Q67TR8 (/IC) Q69TX2 (/IC) Q6AV35 (/IC) Q6Z9R3 (/IC)
(4 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O81313 (/IDA) Q9SA82 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9C707 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...