The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Helix-loop-helix DNA-binding domain
".
FunFam 440: Mnt, isoform J
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
8 | E1JJD1 (/ISS) E1JJE8 (/ISS) M9NDN0 (/ISS) M9NGP0 (/ISS) O46042 (/ISS) Q8SY46 (/ISS) Q9W4Q7 (/ISS) X2JDM5 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
8 | E1JJD1 (/IPI) E1JJE8 (/IPI) M9NDN0 (/IPI) M9NGP0 (/IPI) O46042 (/IPI) Q8SY46 (/IPI) Q9W4Q7 (/IPI) X2JDM5 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
8 | E1JJD1 (/IDA) E1JJE8 (/IDA) M9NDN0 (/IDA) M9NGP0 (/IDA) O46042 (/IDA) Q8SY46 (/IDA) Q9W4Q7 (/IDA) X2JDM5 (/IDA) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
8 | E1JJD1 (/IPI) E1JJE8 (/IPI) M9NDN0 (/IPI) M9NGP0 (/IPI) O46042 (/IPI) Q8SY46 (/IPI) Q9W4Q7 (/IPI) X2JDM5 (/IPI) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
8 | E1JJD1 (/IDA) E1JJE8 (/IDA) M9NDN0 (/IDA) M9NGP0 (/IDA) O46042 (/IDA) Q8SY46 (/IDA) Q9W4Q7 (/IDA) X2JDM5 (/IDA) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | E1JJD1 (/ISS) E1JJE8 (/ISS) M9NDN0 (/ISS) M9NGP0 (/ISS) O46042 (/ISS) Q8SY46 (/ISS) Q9W4Q7 (/ISS) X2JDM5 (/ISS) |
|
Phagocytosis GO:0006909
An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
|
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
|
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
|
Negative regulation of dendrite morphogenesis GO:0050774
Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
|
Detection of temperature stimulus involved in sensory perception of pain GO:0050965
The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
8 | E1JJD1 (/IMP) E1JJE8 (/IMP) M9NDN0 (/IMP) M9NGP0 (/IMP) O46042 (/IMP) Q8SY46 (/IMP) Q9W4Q7 (/IMP) X2JDM5 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | E1JJD1 (/IC) E1JJE8 (/IC) M9NDN0 (/IC) M9NGP0 (/IC) O46042 (/IC) Q8SY46 (/IC) Q9W4Q7 (/IC) X2JDM5 (/IC) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | E1JJD1 (/IDA) E1JJE8 (/IDA) M9NDN0 (/IDA) M9NGP0 (/IDA) O46042 (/IDA) Q8SY46 (/IDA) Q9W4Q7 (/IDA) X2JDM5 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
8 | E1JJD1 (/IDA) E1JJE8 (/IDA) M9NDN0 (/IDA) M9NGP0 (/IDA) O46042 (/IDA) Q8SY46 (/IDA) Q9W4Q7 (/IDA) X2JDM5 (/IDA) |
