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CATH Superfamily 3.90.550.10

Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 64698: Glycosyl transferase family 2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hyaluronan synthase. [EC: 2.4.1.212]
(1) UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-N- acetyl-beta-D-glucosaminyl-(1->4)-(nascent hyaluronan) = UDP + N-acetyl- beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D- glucosaminyl-(1->4)-(nascent hyaluronan). (2) UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D- glucuronosyl-(1->3)-(nascent hyaluronan) = UDP + beta-D-glucuronosyl- (1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)- (nascent hyaluronan).
  • Adds GlcNAc to nascent hyaluronan when the non-reducing end is GlcA, but it adds GlcA when the non-reducing end is GlcNAc.
  • Highly specific for UDP-GlcNAc and UDP-GlcA; no copolymerization is observed if either is replaced by UDP-Glc, UDP-Gal, UDP-GalNAc or UDP-GalA.
 42 A0A0D1AQQ0 A0A0D1B7P3 A0A0D1BG59 A0A0E0UKP3 A0A0E1DZ76 A0A0E1EQN8 A0A0F4VZQ2 A0A0F4W7I9 A0A0F4WP11 A0A0G7D717
(32 more...)
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase. [EC: 2.4.1.101]
UDP-N-acetyl-D-glucosamine + 3-(alpha-D-mannosyl)-beta-D-mannosyl-R = UDP + 3-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl)-beta-D- mannosyl-R.
  • R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor.
  • Note that this enzyme acts before N-acetylglucosaminyltransferases II (EC 2.4.1.143), III (EC 2.4.1.144), IV (EC 2.4.1.145), V (EC 2.4.1.155) and VI (EC 2.4.1.201).
  • Formerly EC 2.4.1.51.
 18 A0A1D8GVQ3 G3K3F9 G3K3G0 G3K3G1 G3K3G2 G3K3G3 G3K3G4 G3K3G5 G3K3G6 G3K3G7
(8 more...)
Protein N-acetylglucosaminyltransferase. [EC: 2.4.1.94]
UDP-N-acetyl-D-glucosamine + [protein]-L-asparagine = UDP + [protein]- N(4)-(N-acetyl-D-glucosaminyl)-L-asparagine.
  • The acceptor is the asparagine residue in a sequence of the form Asn- Xaa-(Ser/Thr).
 11 A0A1C8P8S7 A0A1C8P8T5 A0A1C8P8T6 A0A1C8P8U2 A0A1C8P8Z7 A0A1C8P909 A0A1C8PA33 A0A1C8PA36 I6QKU0 I6QL70
(1 more...)
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