View in Gene3D

CATH Superfamily 3.90.550.10

Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 64376: Probable UTP--glucose-1-phosphate uridylyltransfer...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
UTP--glucose-1-phosphate uridylyltransferase. [EC: 2.7.7.9]
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
    		 127 A0A060T9H7 A0A068JBU5 A0A075B4T3 A0A075E2Q1 A0A084GAV0 A0A097RN49 A0A0A1TVV2 A0A0B2QRD3 A0A0B2RYF1 A0A0B2S9Q2
    (117 more...)
    Threonine ammonia-lyase. [EC: 4.3.1.19]
    L-threonine = 2-oxobutanoate + NH(3).
    • The reaction catalyzed by both types of enzymes involves the initial elimination of water to form an enamine intermediate (hence the enzyme's original classification as EC 4.2.1.16), followed by tautomerization to an imine form and hydrolysis of the C-N bond.
    • The latter reaction, which can occur spontaneously, is also be catalyzed by EC 3.5.99.10.
    • The enzymes from a number of sources also act on L-serine, cf. EC 4.3.1.17.
    • Formerly EC 4.2.1.16.
    		 1 A0A024GQ75
    UTP-monosaccharide-1-phosphate uridylyltransferase. [EC: 2.7.7.64]
    UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.
    • The reaction can occur in either direction and it has been postulated that MgUTP and Mg-diphosphate are the actual substrates.
    • Catalyzes the formation of UDP-Glc, UDP-Gal, UDP-GlcA, UDP-L-Ara and UDP-Xyl, showing broad substrate specificity toward monosaccharide 1-phosphates.
    • Mannose 1-phosphate, L-fucose 1-phosphate and glucose 6-phosphate are not substrates and UTP cannot be replaced by other nucleotide triphosphates.
    		 1 A0A170XLE0
    CATH-Gene3D is a Global Biodata Core Resource Learn more...